Smaller, Better, Faster, Stronger: the “Antibodies” of the Future | Antibodies Mini-Series Part 3

These days, we’re pretty good at harnessing the power of antibodies for medicines and as molecular tools, but they do have some drawbacks. So, cutting-edge researchers are hoping to develop smaller and more stable alternatives, and they’re willing to try just about anything from chopping antibodies up to creating plastic mimics!

Antibodies Series Part 1: https://youtu.be/nKl5RY1-Vwk
Antibodies Series Part 2: https://youtu.be/pFatmpFqWdo

Hosted by: Michael Aranda

SciShow has a spinoff podcast! It’s called SciShow Tangents. Check it out at http://www.scishowtangents.org
———-
Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow
———-
Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever:

Silas Emrys, Charles Copley, Jb Taishoff, Jeffrey Mckishen, James Knight, Christoph Schwanke, Jacob, Matt Curls, Christopher R Boucher, Eric Jensen, LehelKovacs, Adam Brainard, Greg, Ash, Sam Lutfi, Piya Shedden, KatieMarie Magnone, Scott Satovsky Jr, charles george, Alex Hackman, Chris Peters, Kevin Bealer

———-
Looking for SciShow elsewhere on the internet?
Facebook: http://www.facebook.com/scishow
Twitter: http://www.twitter.com/scishow
Tumblr: http://scishow.tumblr.com
Instagram: http://instagram.com/thescishow
———-
Sources:
Antibodies as Medicines
https://pubmed.ncbi.nlm.nih.gov/29973504/
https://doi.org/10.2165/00003088-199528020-00004
Antibody Fragments
https://pubmed.ncbi.nlm.nih.gov/20093855/
https://pubmed.ncbi.nlm.nih.gov/31544842/
https://doi.org/10.1155/2012/980250
Mini-Binders
https://doi.org/10.1038/nature23912
https://doi.org/10.1126/science.abd9909
https://doi.org/10.1016/j.tibs.2019.12.008
https://doi/org/10.1126/science.aaz8818
Plastic Antibodies
https://doi.org/10.1021/ja102148f
https://doi.org/10.1016/j.snb.2011.07.039
https://doi.org/10.1038/srep26132
https://doi.org/10.1002/anie.201602076
https://doi.org/10.1002/(SICI)1520-636X(1998)10:3%3C195::AID-CHIR1%3E3.0.CO;2-9

Images:
https://science.sciencemag.org/content/370/6515/426
https://www.istockphoto.com/photo/llama-up-close-gm1209120485-349767631
https://www.istockphoto.com/photo/3d-render-antibodies-identify-and-neutralize-pathogen-virus-over-black-background-gm1222559388-358781728
https://www.istockphoto.com/photo/antibodies-destroy-an-infected-cell-by-a-virus-immun-defense-kill-the-infected-cell-gm1218459794-356049018
https://www.istockphoto.com/photo/young-woman-having-a-nasal-swab-test-gm1266490168-371290691
https://www.istockphoto.com/photo/eerie-light-radiating-from-tip-of-needle-of-medical-syringe-gm1291953530-386917452

Leave a comment

Your email address will not be published. Required fields are marked *